The first Cathedral of Nicastro, according to tradition, was built in the Byzantine period with the title of the Assumption, but we don't know the exact location. In 1100 the Countess Eremburga, nephew of Robert the Guiscard built a new cathedral and dedicated it to SS. Peter and Paul, in a majestic romanesque-style, at the confluence of the "Piazza" and "Canne's rivers" (in the area between the Church of the Crucifixion and the "Maggiore Perri" primary school now).

This building collapsed during the earthquake in 1638 and in 1640 the Archbishop Thomas Perrone began the construction of a new cathedral in the actual site.

Between 1693 and 1702 was built the wooden choir, enlarged and completed in 1731 by Bishop Angeletti.

After decades of decline was provided by the work of Bishop Pellegrini to a redevelopment of the sacred building with the interior work and renovation liturgical furnishings.

Between 1825 and 1854 Bishop Berlingeri reconfigured the interior expanding it with the increase of the times, instead of the flat ceiling ruined, with the extension of the transept ended with two apses and with the construction of two additional chapels in aisles.

At the end of the 800 seventeenth-century facade totally lost its architectural character with the remodeling of the prospectus which was further changed in 1925 with its current configuration. In 1935 hit was erected the dome covered with tiles and half of the 900 was built this staircase. In 1969 it was transformed the priesthood, removing the marble altar of the first half of 800, the wrought-iron gate, the bishop's throne and narrowing the seventeenth-century wooden choir.